NMR Core Facility at UCD

Here you will find information about the facilities available, a brief introduction to NMR, the sort of information can get from it and how can it help your research.

Introduction and History

Nuclear Magnetic Resonance (NMR) spectroscopy is a technique that provides high resolution information about the structure and dynamics of molecules in solution at the atomic level. It used to study a wide variety of molecules from small drug like molecules to macromolecules such as proteins and nuceic acids.

The NMR Core facilities provideaccess to state of the art instrumentation to researchers at UCD and its affiliated institutions for the study of the structure and function of biological macromolecules. NMR core staff and faculty provide assistance to other users through training or through the development of collaborations.

The NMR core was established in 1996 through a grant from the Howard Hughes Medical Institue and the National Cancer Institute. Ongoing support for the NMR facility is provided primarily by the University of Colorado Cancer Center and the School of Medicine.

The NMR facility is located in Room L18-1300 on the first floor of the RC-1 South Building on UCD campus at the Anschutz Medical campus.

The facility has Varian INOVA spectrometers operating at 500 MHz and 600 MHz, and an 800 MHz NMR spectrometer, which is located at the UC Boulder campus. Recently a 900 MHz spectrometer was installed in the facility as part of the Rocky Mountain Regional NMR Resource. A variety of probes are available that are suitable for the solution NMR studies of biological macromolecules including proteins, nucleic acids and carbohydrates. There is a small wet lab that can be used for sample manipulations, and an office/computer room for visitors while using the facility.

Information on access to the core, user fees, documentation etc, can be found through the links at the top of this page.